Genotropin is a high quality growth hormone from the world famous manufacturer Pfizer. This drug is a synthetic version of GH, which has full similarity (both structural and functional) with natural GH, which is secreted in the anterior pituitary lobe. Growth hormone itself supports normal metabolism and body composition in adults and is responsible for the growth of children and adolescents.
The use of somatropin has been shown to have anabolic effects that allow building muscle mass and lean body mass, burning fat, reducing the time required for the regeneration of wounds and injuries, improving the quality of life of the elderly (due to its ability to rejuvenate the body), improving anaerobic performance and much more. That is why buying Genotropin from Pfizer will help yu to become better version of yourself.
Mechanism of Action
Somatropin, like natural GH, binds to the GHR receptor, which is a transmembrane protein. Scientific literature analysis showed that at first, only IGF-1 (insulin-like growth factor type 1) was thought to mediate anabolic action of GH, however, later studies showed that the growth hormone itself has anabolic and anti-catabolic effect on the protein, but it is less expressed than that of IGF-1. The action of somatropin decreases the tissue sensitivity to insulin and enhances blood glucose synthesis, while increasing fat burning (it raises the level of FFA and triglycerides in the blood), thus transferring the body to the fat way of energy production. These effects lead to the insulin secretion, which, together with GH, promotes the IGF-1 secretion. IGF-1 is also synthesized in muscle and a number of other peripheral tissues, where it acts in a paracrine and autocrine manner, but studies have shown that some of the IGF-1 synthesized in peripheral tissues still enters the bloodstream. On muscle cells, there is both an IGF-1 receptor, an insulin receptor, and a hybrid receptor (on which IGF-1 and insulin can act with equal force), also insulin and IGF-1 can bind to each other’s receptors due to structural similarity, but they do so less efficiently. Unlike growth hormone, IGF-1 has insulin-like activity and can induce glucose, FFA and amino acid uptake by cells. Increased levels of glucose and free fatty acids are necessary for the anabolic IGF-1 action because the powerful induction of protein synthesis needs many energy sources. Insulin itself has its own anabolic and anti-catabolic activity. Thus, we can say that the action of the growth hormone is the combined action of the growth hormone itself, insulin and IGF-1.
The IGF-1 action not only induces protein synthesis and prevents its degradation, but also leads to cell division and differentiation (which is particularly important in childhood); IGF-1 activity also increases bone mineralization, accelerates joints, ligaments and cartilage regeneration and generally accelerates tissue regeneration throughout the body. That is why many athletes are looking for where to buy Genotropin online.
Effects
– growth muscle tissue growth;
– Increased rate of lipolysis and utilization of free fatty acids and triglycerides as an energy source;
– acceleration of tissue regeneration;
– bone strength increase;
– muscle fascia, joints, cartilage, and ligaments improvement;
– skin density and elasticity improvement;
– strengthening of the anaerobic pathway of energy synthesis;
– sleep quality improvement.
How to use
Genotropin is injected subcutaneously, and the daily dose for muscle growth is 10 IU per day (initial dose is 3-4 IU) for a duration of 12 weeks; if you want to improve your results and decrease the risk of side effects (edema and tunnel syndrome), it is advisable to stop at a dose of 6-7 IU, but increase using duration up to 24 weeks. For fat burning effect, use the drug in a dose of 5 IU per day for at least 12 weeks. You can find the best Genotropin for sale in our store, and you`ll be pleasantly surprised by Genotropin prices.
